Ricardo Villa-Bellosta Selected Research

6- N,N- diethyl- beta,gamma- dibromomethylene- D- ATP

11/2019

ATP-based therapy prevents vascular calcification and extends longevity in a mouse model of Hutchinson-Gilford progeria syndrome.

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Ricardo Villa-Bellosta Research Topics

Disease

25	Vascular Calcification 05/2022 - 05/2007
5	Progeria (Hutchinson Gilford Syndrome) 10/2020 - 06/2013
4	Hyperphosphatemia 12/2021 - 05/2007
4	Atherosclerosis 01/2019 - 06/2013
3	Premature Aging 10/2020 - 06/2013
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 01/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2020 - 06/2013
2	Chronic Renal Insufficiency 01/2019 - 05/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 01/2016
2	Calcinosis 01/2017 - 11/2015
2	Hypertension (High Blood Pressure) 01/2016 - 04/2015
1	Atherosclerotic Plaque (Atheroma) 12/2021
1	Vascular Diseases (Vascular Disease) 01/2019
1	Renal Insufficiency (Renal Failure) 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Failure to Thrive 01/2018
1	Diabetes Mellitus 01/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2016
1	Hyperlipidemias (Hyperlipidemia) 01/2016
1	Alkalosis 01/2016
1	ST Elevation Myocardial Infarction 01/2016
1	Cardiomegaly (Heart Hypertrophy) 04/2015
1	Stroke (Strokes) 06/2013
1	Myocardial Infarction 06/2013
1	Neoplasms (Cancer) 08/2010
1	Acidosis 02/2010
1	Necrosis 09/2007
1	Insulin Resistance 09/2007
1	Dyslipidemias (Dyslipidemia) 09/2007

Drug/Important Bio-Agent (IBA)

13	diphosphoric acid (pyrophosphoric acid)IBA 05/2022 - 07/2011
9	calcium phosphateIBA 12/2021 - 01/2011
8	Phosphates (Orthophosphate)IBA 12/2021 - 05/2007
6	Adenosine Triphosphate (ATP)IBA 05/2022 - 01/2013
5	Durapatite (Hydroxylapatite)IBA 12/2021 - 01/2015
3	EnzymesIBA 05/2022 - 08/2010
3	Phosphorus (Red Phosphorus)IBA 12/2021 - 01/2015
3	Alkaline PhosphataseIBA 01/2019 - 06/2013
2	MagnesiumIBA 10/2020 - 01/2017
2	ApolipoproteinsIBA 01/2019 - 01/2018
2	Lamin Type A (Lamin A)IBA 01/2019 - 06/2013
2	Apolipoproteins E (ApoE)IBA 11/2018 - 01/2018
2	CalciumIBA 01/2017 - 01/2017
2	Diphosphonates (Bisphosphonates)IBA 01/2013 - 01/2009
1	Glutathione (Reduced Glutathione)IBA 10/2020
1	NADP (NADPH)IBA 10/2020
1	AntioxidantsIBA 10/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2020
1	SaltsIBA 01/2020
1	Levamisole (Decaris)FDA Link 11/2019
1	6- N,N- diethyl- beta,gamma- dibromomethylene- D- ATPIBA 11/2019
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2019
1	Acetates (Acetic Acid Esters)FDA Link 01/2019
1	Citric Acid (Citrate)FDA LinkGeneric 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 11/2018
1	Proteins (Proteins, Gene)FDA Link 01/2018
1	LipidsIBA 01/2018
1	Dialysis SolutionsIBA 01/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2016
1	Calcifediol (Calcidiol)FDA Link 01/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2016
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2016
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2016
1	pro-brain natriuretic peptide (1-76)IBA 01/2016
1	ectonucleotide pyrophosphatase phosphodiesterase 1IBA 01/2016
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 04/2015
1	Angiotensin IIIBA 04/2015
1	PolyphosphatesIBA 01/2013
1	NucleotidesIBA 01/2013
1	Phosphate Transport Proteins (Phosphate Transporter)IBA 10/2012
1	PyrophosphatasesIBA 07/2011
1	ArsenicIBA 08/2010
1	MetalloidsIBA 08/2010
1	sodium phosphate (trisodium phosphate)FDA LinkGeneric 02/2010
1	Foscarnet FDA LinkGeneric 01/2009
1	Annexin A5IBA 09/2007
1	Ethidium (Ethidium Bromide)IBA 09/2007
1	DNA (Deoxyribonucleic Acid)IBA 09/2007
1	Acridine OrangeIBA 09/2007
1	ThiazolidinedionesIBA 09/2007
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 09/2007
1	PPAR alphaIBA 09/2007
1	Fibric Acids (Fibrates)IBA 09/2007
1	Caspase 3 (Caspase-3)IBA 09/2007

Therapy/Procedure

4	Renal Dialysis (Hemodialysis) 01/2019 - 01/2016
2	Therapeutics 11/2019 - 01/2018
1	Carotid Endarterectomy 11/2018